DP4114 × MON 810 × MIR604 × NK603

GM event

DP4114 × MON 810 × MIR604 × NK603

Unique identifier code

DP-ØØ4114-3 x MON-ØØ81Ø-6 x SYN-IR6Ø4-5 x MON-ØØ6Ø3-6

Original application

RP-1506

Authorisation holder

(1) The name and address of the authorisation holder is Corteva Agriscience LLC, 9330 Zionsville Road, Indianapolis, Indiana 46268-1054, USA. (2) The authorisation holder is represented in Great Britain by Corteva Agriscience UK Limited, Unit H4, Building H Melbourn Science Park, Cambridge Road, Melbourn, Cambridgeshire, UK, SG8 6HB

Characteristics

The genetically modified maize DP-ØØ4114-3 expresses the pat gene, which confers tolerance to glufosinate ammonium-based herbicides and the cry1F, the cry34Ab1 and cry35Ab1 genes, which confer resistance to certain lepidopteran and certain coleopteran pests.
The genetically modified maize MON-ØØ81Ø-6 expresses the cry1Ab gene, which confers resistance to certain lepidopteran pests.
The genetically modified maize SYN-IR6Ø4-5 expresses the mcry3A gene, which confers resistance to certain coleopeteran pests. In addition, the pmi gene, coding for the PMI protein, was used as a selection marker in the genetic modification process.
The genetically modified maize MON-ØØ6Ø3-6 expresses the CP4 epsps and the CP4 epsps L214P genes, which confer tolerance to glyphosate-based herbicides.

Detection method

For DP-ØØ4114-3, the document entitled “Event-specific Method for the Quantification of maize DP-ØØ4114-3 by Real-time PCR”, reference “EURL-VL-02/14VP” and published 11 April 2018;  
For MON-ØØ81Ø-6, the document entitled “CRL assessment on the validation of an event specific method for the relative quantitation of maize line MON 810 DNA using real-time PCR as carried out by Federal Institute for Risk Assessment (BfR)”, reference “CRL-VL-25/04VR” and dated 10 March 2006; 
For SYN-IR6Ø4-5, the document entitled “Event-specific Method for the Quantification of Maize Line MIR604 Using Real-time PCR”, dated 03 April 2007, reference “CRLVL04/05VP corrected version 1 30/03/2010”;
For MON-ØØ6Ø3-6, the document entitled “Event-specific method for the quantitation of maize line NK603 using real-time PCR”, reference “CRLVL27/04VP” and published 10 January 2005. Validated by the EU Reference Laboratory established under Regulation (EC) No 1829/2003, published at https://gmo-crl.jrc.ec.europa.eu/method-validations

Commodity

Maize

Authorised use

(a) foods and food ingredients containing, consisting of, or produced from genetically modified maize referred to in paragraph 1; (b) feed containing, consisting of, or produced from genetically modified maize referred to in paragraph 1; (c) products containing or consisting of genetically modified maize referred to in paragraph 1 for uses other than those provided for in sub-paragraphs (a) and (b), with the exception of cultivation.